姓 名:陈景
职 称:教授,博士生导师
E-mail:jingchen3236@njucm.edu.cn
主 要 研 究 方 向:
基于中药药性理论的中药药效物质基础发掘
中西医结合抗肿瘤研究
个 人 简 介
陈景,江苏省特聘教授,博士生导师。2017年博士毕业于苏州大学(导师:钟志远和邓超教授),2018年至2021年,在美国康奈尔大学开展博士后研究(合作导师:马明林教授),2021年以特聘教授引进717银娱geg优越会工作。2022年入选江苏省特聘教授和第八届中国科协青年人才托举工程。自2021年起担任Asian Journal of Pharmaceutical Sciences、Cancer Innovation、Acta Materia Medica、Traditional Medicine Research和Biomedical Engineering Communications五本期刊青年编委。并担任中华中医药学会中药实验药理分会青年委员、中国康复医学会药学与康复专业委员会委员和中国中医药研究促进会中药雾化专业委员会常务委员等职务。已在Nature Food、Nature Communications和Advanced Materials等权威期刊发表论文20余篇,谷歌学术总引用1600余次。此外申请了多项中国专利和2项美国专利,其中申请的一项美国专利已实现产业转化。曾获得2017 Baxter China Young Investigator Award一等奖,2023年全国商业科技进步奖一等奖。
承 担 的 主 要 科 研 项 目
中国科协青年人才托举工程项目,主持,在研
江苏省特聘教授基金,主持,在研
国家自然科学基金青年项目,主持,在研
葡聚糖凝胶包载植物精油纳米乳对糠秕马色拉菌所致特应性皮炎的研究(横向),主持,结题。
代 表 性 论 文
B. Wang#*, J. Chen#, J.S. Caserto#, X. Wang and M. Ma*. An in situ hydrogel-mediated chemo-immunometabolic cancer therapy. Nature Communications, 2022, 13(1): 1-13.
J. Chen, J.S. Caserto, I. Ang, K. Shariati, J. Webb, B. Wang, X. Wang, N. Bouklas and M. Ma*. An adhesive and resilient hydrogel for the sealing and treatment of gastric perforation. Bioactive Materials, 2021, 14: 52-60.
J. Chen#, B. Wang#*, J.S. Caserto, K. Shariati, P. Cao, Y. Pan, Q. Xu and M. Ma*. Sustained Delivery of SARS‐CoV‐2 RBD Subunit Vaccine using a High Affinity Injectable Hydrogel Scaffold. Advanced Healthcare Materials, 2021: 2101714.
J. Chen, J. Webb, K. Shariati, S. Guo, J. K. Montclare, S. McArt, and M. Ma*. Pollen-mimicking, enzyme-loaded microparticles to reduce organophosphate toxicity in managed pollinators. Nature Food. 2021, 2, 339-347. (Cover paper)
J. Chen, D. Wang, L. -H. Wang, W. Liu, A. Chiu, K. Shariati, Q. Liu, X. Wang, Z. Zhong, J. Webb, R. E. Schwartz, N. Bouklas and M. Ma*. An adhesive hydrogel with “load-sharing” effect as tissue bandages for drug and cell delivery. Advanced Materials. 2020, 2001628.
J. Chen, H. He, C. Deng*, L. Yin and Z. Zhong*. Saporin-loaded CD44 and EGFR dual-targeted nanogels for potent inhibition of metastatic breast cancer in vivo. International Journal of Pharmaceutics, 2019, 560: 57-64.
J. Chen, K. Huang, Q. Chen, C. Deng*, J. Zhang and Z. Zhong*. Tailor-making fluorescent hyaluronic acid microgels via combining microfluidics and photoclick chemistry for sustained and localized delivery of herceptin in tumors. ACS Applied Materials & Interfaces, 2018, 10(4): 3929-3937.
J. Chen, J. Ouyang, Q. Chen, C. Deng*, F. Meng*, J. Zhang, R. Cheng, Q. Lan and Z. Zhong*. EGFR and CD44 dual-targeted multifunctional hyaluronic acid nanogels boost protein delivery to ovarian and breast cancers in vitro and in vivo. ACS Applied Materials & Interfaces, 2017, 9(28): 24140-24147.
J. Chen, Y. Zou, C. Deng*, F. Meng, J. Zhang and Z. Zhong*. Targeted and potent cancer protein therapy using bioresponsive fluorescent click nanogels. Journal of Controlled Release, 2017, 259: e65.
J. Chen, Y. Zou, C. Deng*, F. Meng, J. Zhang and Z. Zhong*. Multifunctional click hyaluronic acid nanogels for targeted protein delivery and effective cancer treatment in vivo. Chemistry of Materials, 2016, 28(23): 8792-8799.