姓名:王若宁
职称:教授 博士研究生导师
E-mail:ruoningw@njucm.edu.cn
主要研究方向:
围绕中枢神经系统的治疗瓶颈和中药多组分的递送问题,聚焦中药多组分脑靶向仿生递送系统的研究,包括中药多组分高效治疗脑胶质瘤的研究和脑靶向仿生递送系统的设计。
个人简介
王若宁,博士,717银娱geg优越会教授、博士研究生导师,校团委兼职副书记,全国中医药青年国医精英(2022),入选江苏省“333高层次人才培养工程”、江苏省科协青年科技人才托举工程、中华中医药学会青年人才托举工程(A类),获江苏省青年颗粒学奖。聚焦中药多组分脑靶向仿生递送系统的研究,主持国家自然科学基金(面上、青年)等国家级、省级、厅局级项目十余项,以第一或通讯作者发表ACS nano,Journal of Controlled Release(4篇),Bioactive Materials,Acta Pharmaceutica Sinica B,Nano Today,Small, Biomaterials , Chemical Engineering Journal等高水平论文30余篇,其中IF>10分16篇,高被引文章2篇,封面文章3篇;申请并公开国家专利14项,其中授权8项,PCT 1项。(统计截止至2024年4月)
现任世界中医药学会联合会经皮给药专业委员会理事、中国颗粒学会青年理事、中华中医药学会中药制剂分会委员、中药毒理学与安全性研究分会委员等,任《Asian Journal of Pharmaceutical Sciences》、中草药中英双刊、《南京中医药大学学报》等期刊青年编委,参编江苏省高等学校重点教材《工业药剂学》、《中药药剂学》等。
指导学生获江苏省优秀硕士学位论文(2人次),省级优秀本科毕业论文一等奖、省级二等奖,连续两年获得省级优秀毕业论文团队奖。作为第一指导教师指导学生荣获第十八届“挑战杯”全国大学生课外学术科技作品竞赛国赛二等奖、江苏省选拔赛一等奖和二等奖,第八届江苏省“互联网+”大学生创新创业大赛二等奖,入选第十六届全国大学生创新创业年会改革成果展示项目,受邀参加第十六届全国大学创新创业年会。
代表性论文
1. Jiwei Cui‡, Xue Wang‡, Jinge Li, Anran Zhu, Yingjiang Du, Wei Zeng, Yumiao Guo, Liuqing Di, Ruoning Wang*.Immune exosomes loading self-assembled nanomicelles traverse the blood-brain barrier for chemo-immunotherapy against glioblastoma.ACS Nano,2023, 17: 1464-1484
2. Ruoning Wang, Xiaohong Wang, Junsong Li, Liuqing Di, Jianping Zhou*, Yang Ding*. Lipoprotein-biomimetic nanostructure enables tumor-targeted penetration delivery for enhanced photo-gene therapy towards glioma. Bioactive Materials, 2022, 13: 286-299
3. Jiale Li, Hanwen Zhang, Yingyu Jiang, Nengjin Li, Anran Zhu, Yingjie Zhang, Kuanhan Feng, Wei Zeng, Liuqing Di*, Ruoning Wang*. The landscape of extracellular vesicles combined with intranasal delivery towards brain diseases. Nano Today, 2024,55: 102169
4. Jinge Li‡, Xiaohong Wang‡, Yumiao Guo‡, Yingjie Zhang, Anran Zhu, Wei Zeng, Liuqing Di, Ruoning Wang*. Ginsenoside Rg3-engineered exosomes as effective delivery platform for potentiated chemotherapy and photoimmunotherapy of glioblastoma. Chemical Engineering Journal, 2023, 471: 144692
5. Jiwei Cui, Yuanxin Xu, Haiyan Tu, Huacong Zhao, Honglan Wang, Liuqing Di, Ruoning Wang*. Gather wisdom to overcome barriers:Well-designed nano-drug delivery systems for treating gliomas. Acta Pharmaceutica Sinica B, 2022, 12: 1100-1125
6. Ruoning Wang‡*, Xue Wang‡, Huacong Zhao‡, Nengjin Li, Jiale Li, Hanwen Zhang, Liuqing Di*. Targeted delivery of hybrid nanovesicles for enhanced brain penetration to achieve synergistic therapy of glioma. Journal of Controlled Release, 2024, 365: 331-347
7. Ruoning Wang‡*, Xinru Zhang‡, Jianyu Huang‡, Kuanhan Feng, Yingjie Zhang, Jie Wu, Lei Ma, Anran Zhu, Liuqing Di*. Bio-fabricated nanodrugs with chemo-immunotherapy to inhibit glioma proliferation and recurrence. Journal of Controlled Release, 2023, 354: 572-587
8.Ruoning Wang‡*, Xiaohong Wang‡, Yuting Zhang, Huacong Zhao, Jiwei Cui, Junsong Li*, Liuqing Di*. Emerging prospects of extracellular vesicles for brain disease theranostics. Journal of Controlled Release, 2022, 341: 844-868
9. Ruoning Wang, Chenshuang Zhang, Junsong Li, Jinyu Huang, Yaw Opoku-Damoah, Bo Sun, Jianping Zhou, Liuqing Di*, Yang Ding*. Laser-triggered polymeric lipoproteins for precision tumor penetrating theranostics. Biomaterials. 2019, 221: 119413
10. Ruoning Wang,Yue Han, Bo Sun,Ziqiang Zhao,Yaw Opoku-Damoah, Hao Cheng,Huaqing Zhang, Jianping Zhou*, Yang Ding*. Deep tumor penetrating bioparticulates inspired burst intracellular drug release for precision chemo-phototherapy. Small,2018, 14: 1703110